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Risks during PICC line placement While the PICC line is being placed, possible risks include: Puncture of a blood vessel Blood clots forming in the vein Irregular heartbeat Nerve injury Infection Allergic reaction to contrast (x-ray dye) if used Risks after PICC line placement After the PICC line is placed, possible complications include: Blood clots Movement of the PICC line out of position Inflammation or irritation of the vein Infection Important information Serious problems are rare, but they can happen

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